Black Cobra 125 in Gujranwala
Generic Name: Sildenafil Citrate
Cobra works by increasing the effects of nitric oxide (NO),
a substance that serves many key functions in biological processes throughout
the body. One of the most well known and important functions of NO is the
dilation of blood vessels. This allows greater blood flow to the muscles, which
of course can be valuable to an athlete during competition.
What is more interesting to me is the role of NO on muscles
during resistance training. JE Anderson found that NO appears to be a vital
signal in the activation of muscle satellite cells in response to damage.
Satellite cell activation is the key first step in the repair and hypertrophy
of muscle cells after heavy training. It may therefore enhance the hypertrophy
response to exercise, working at the most basic and primary level of the
process.
In addition to this, there is evidence that suggests that
Viagra may work to amplify the "pump" response during training. The
pump is thought to happen when contracting muscle fibers signal local vascular
relaxation (increasing the blood flow to the working muscles). According to KS
Lau and coworkers, NO generated by neuronal NO synthase in contracting skeletal
muscle fibers may regulate vascular relaxation via a cGMP-mediated pathway.
Since the mechanism of action for Viagra is amplification of the cGMP pathway,
there is ample reason to believe that the drug may indeed affect the blood flow
and pump to the muscle, and therefore indirectly aid in the hypertrophy
response.
Common uses and directions for Sildenafil Citrate:
Normally nerves or blood vessels in men with male erectile
dysfunction do not work properly, which prevents them from achieving an
erection. It works to restore the blood flow to the penis making it easier to
achieve and sustain longer erections.
It increases the
blood flow to the penis by helping the arteries in the penis relax and expand.
As the arteries in the penis expand and harden, veins that normally carry away
blood flow to the penis are compressed resulting in an erection.
It takes at least 30
minutes before it starts to work, and remains active for up to 4 hours. The
erection goes away after intercourse.
Men who are currently using medicines that contain nitrates,
such as nitroglycerin should not use it because taken together they can lower
the blood pressure too much. Cobra should not be used by women or children.
Sildenafil Citrate additional information:
Common uses
is used to treat
erection difficulties, such as erectile dysfunction (ED).
Directions
comes as a tablet
containing 150 mg. sildenafil citrate, to take by mouth.
For most men, the recommended dose is 50 mg. taken, as
needed, approximately 1 hour before sexual activity. However, sildenafil
citrate may be taken anywhere from 4 hours to 0.5 hour before sexual activity.
Based on effectiveness and toleration, the dose may be increased to a maximum
recommended dose of 100 mg or decreased to 25 mg. The maximum recommended
dosing frequency is once per day.
Precautions
A starting dose of 25 mg. should be considered individuals
of the age 65+ and in individuals with hepatic impairment or severe renal
impairment.
Given the extent of the interaction with patients receiving
concomitant therapy with ritonavir, it is recommended not to exceed a maximum
single dose of 25 mg. of Viagra in any 48 hour period.
Sildenafil citrate potentiates the hypotensive effects of
nitrates and its administration in patients who use nitric oxide donors or
nitrates in any form is therefore contraindicated.
Treatments for erectile dysfunction, including Kobra/Viagra,
should not be generally used in men for whom sexual activity is inadvisable
because of their underlying cardiovascular status.
Patients who have suffered a myocardial infarction, stroke,
or life-threatening arrhythmia within the last 6 months, patients with resting
hypotension or hypertension, patients with cardiac failure or coronary artery
disease and patients with retinitis pigmentosa should use Kobra/Viagra with
great caution.
The safety of Viagra is unknown in patients with bleeding
disorders and patients with active peptic ulceration.
Cobra/Viagra should be used with caution by individuals with
anatomical deformation of the penis and by individuals who have conditions
which may predispose them to priapism.
The safety and efficacy of combinations of Viagra with other
treatments for erectile dysfunction have not been studied. Therefore, the use
of such combinations is not recommended.
Possible side effects
The most frequently observed side effects of Cobra/Viagra
includes headache, flushing, dyspepsia and nasal congestion.
Less frequent side effects include erections that will not
go away and vision changes. In the event that an erection persists longer than
4 hours, seek immediate medical assistance. Other less frequent side effects
include urinary tract infection, abnormal vision, diarrhea, dizziness and rash.
If you notice other effects not listed above, contact your
doctor.
Overdose
If overdose of Cobra/Viagra is suspected, contact your local
poison control center or emergency room immediately.
Additional information
Keep Viagra/Cobra in a tightly closed container and out of
reach of children. Store at room
temperature and away from excess heat and moisture (not in the bathroom).
Note
The above information is intended to supplement, not
substitute for, the expertise and judgment of your physician, or other
healthcare professional. It should not be construed to indicate that use of
Viagra is safe, appropriate, or effective for you. Consult your healthcare professional
before using Viagra/Cobra
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